BIOL1040 - Prin & Issues Human Heredity
This course begins with a discussion of how heredity changed in the 18th and 19th centuries. Darwinian and Mendelian theories are presented. A thorough discussion of cells, chromosomes, and cell division is followed by an analysis of the transmission of genes from generation to generation as exemplified by Mendel=s laws. Pedigree analysis and human genetics are explained by dominant and recessive traits, sex-linked inheritance, and genetic maps. Cytogenetics occupies a large section of the course. Polyploidy, aneuploidy, Klinefelter and Turner syndromes are examined. Human reproduction and embryology are studied. DNA structure, the genetic code, and manufacture of proteins are highlights. Metabolic disorders such as phenylketonuria, sickle cell anemia, and the thalassemia are discussed. Mutation, recombinant DNA, and its application are followed by a discussion of genes, cancer, and the immune system. Population genetics, human diversity and evolution, and genetic screening and counseling conclude the course. Principles of scientific inquiry are integrated throughout the course.
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